Buy Chloramphenicol

Catalog Antibiotics

Availability: In Stock (29 packs)

Active Ingredient: Chloramphenicol

Manufacturer: Cipla Limited / Nicholas Piramal India Ltd.

Disease(s): Respiratory infections / ear infections.

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Chloramphenicol is a broad spectrum antibiotic effective against most gram-positive and gram negative bacteria. It has a bactericidal effect, is active against pathogens of various purulent and inflammatory processes.

250MG
Product name Per Pill Savings (only today) Per Pack
60 pills $0.82 $49.25 ADD TO CART
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360 pills $0.46 $130.01 $295.48 $165.47 ADD TO CART

Instructions for use

Chloramphenicol is an antibacterial drug used in the treatment of various infections, including in ophthalmology and pediatrics.

Chloramphenicol is available in various forms: in the form of tablets, eye drops, liniment and powder for the preparation of a solution for injection.

Chloramphenicol is a broad-spectrum antibiotic. The antimicrobial effect of the drug is based on a violation of the synthesis of proteins of various microorganisms.

It is active against gram-positive bacteria: Streptococcus spp., Staphylococcus spp .; Gram-negative bacteria: Escherichia coli, Neisseria gonorrhoeae, Proteus spp., Haemophilus influenzae, Neisseria meningitidis, Rickettsia spp., Salmonella spp., Serratia spp., Shigella spp., Klebsiella spp., Yersinia spp .; against Spirochaetaceae, individual large viruses.

Indications for use of chloramphenicol

According to the instructions, chloramphenicol is prescribed for oral administration with:

  • typhoid fever;
  • brucellosis;
  • paratyphoid;
  • tularemia;
  • typhus;
  • dysentery;
  • whooping cough;
  • trachoma;
  • meningitis;
  • osteomyelitis;
  • sepsis
  • pneumonia;
  • generalized salmonellosis;
  • rickettsiosis.

This drug can be used for therapy and other infectious diseases caused by microorganisms sensitive to it. Chloramphenicol is also used in case of ineffectiveness of treatment with other antibiotics or the impossibility of their use in the patient due to hypersensitivity to them.

Contraindications

According to the instructions, chloramphenicol is not prescribed for:

  • severe symptoms of liver dysfunction;
  • blood diseases;
  • skin diseases such as eczema, psoriasis, fungal diseases;
  • glucose-6-phosphate dehydrogenase enzyme deficiency;
  • pregnancy and lactation;
  • hypersensitivity of the patient to chloramphenicol, azidamphenicol, tiamphenicol;

as well as in children under 4 weeks.

Method of use and dosage of chloramphenicol

The dosage regimen of the drug is set individually.

Ingestion:

  • adults – 3-4 times a day;
  • children under 3 years old – 3-4 times a day, 15 mg per kg of weight;
  • 3-8 years – 3-4 times a day for 150-200 mg;
  • over 8 years old – 3-4 times a day for 200-400 mg.

The duration of chloramphenicol therapy is 7-10 days.

Pregnancy and lactation

An overdose of the drug is manifested by cardiovascular (“gray”) syndrome in newborns and premature babies during high-dose therapy due to the accumulation of chloramphenicol, which is due to the immaturity of liver enzymes and its direct toxic effect on the myocardium.

Cardiovascular syndrome is manifested by a bluish-gray skin color, a decrease in body temperature, a lack of reactions, irregular breathing, and cardiovascular failure. In this case, mortality is about 40%.

For the treatment of an overdose of chloramphenicol, hemosorption and symptomatic therapy are used.

Pregnancy and lactation

An overdose of the drug is manifested by cardiovascular (“gray”) syndrome in newborns and premature babies during high-dose therapy due to the accumulation of chloramphenicol, which is due to the immaturity of liver enzymes and its direct toxic effect on the myocardium.

Cardiovascular syndrome is manifested by a bluish-gray skin color, a decrease in body temperature, a lack of reactions, irregular breathing, and cardiovascular failure. In this case, mortality is about 40%.

For the treatment of an overdose of chloramphenicol, hemosorption and symptomatic therapy are used.

Special instructions

The drug should not be used in newborns due to the danger of developing a “gray syndrome”.

During therapy with this antibiotic, the patient needs regular monitoring of the peripheral blood picture.

Chloramphenicol and synonyms Chloramphenicol should be used with caution in patients previously treated with cytostatics or radiation therapy.

During treatment with the drug, alcohol should be avoided, since a disulfiram-like reaction can develop, manifested by skin hyperemia, nausea, tachycardia, vomiting, reflex cough, convulsions.

Chloramphenicol is not recommended for the treatment of tonsillitis, acute respiratory infections, any infections that occur in a mild form, as well as use it for prevention.

Side effects of chloramphenicol

Chloramphenicol and synonyms Chloramphenicol can cause side effects.

Digestive system: flatulence, diarrhea, nausea, vomiting.

Hematopoietic system: leukopenia, thrombocytopenia, aplastic anemia, agranulocytosis.

CNS and peripheral nervous system: optic neuritis, peripheral neuritis, depression, headache, delirium, confusion, auditory and visual hallucinations.

Local reactions: irritation with local or external use.

Allergic reactions: urticaria, rash on the skin, angioedema.

Where to buy chloramphenicol

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